There’s so much good stuff in this responsive design interview with Brad Frost and others. I was especially interested in everyone’s thoughts on responsive frameworks. Here’s Aaron Gustafson‘s answer:

I find Foundation, Bootstrap, and similar frameworks interesting from an educational standpoint, but I would never use one when building a production site. For prototyping a concept, sure, but to take one of these into production you need to be rigorous in your removal of unused CSS and JavaScript or you end up creating a heavy, slow experience for you users. I also think you need to work twice as hard to break out of the theme of the framework. There are a ton of Bootstrap sites out there that look like Bootstrap sites. Your design should be as unique as your product, not some off the shelf thing you just changed some colors on.

Agreed.